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What is HIPEC?

What is HIPEC?

Following the removal of the abdominal membrane regions where the cancer is placed, the operation which includes applying a heated chemotherapic fluid into the abdominal cavity is called hyperthermic intraperitoneal chemotherapy (HIPEC).

The HIPEC treatment strives to radically remove all cancer cells from the abdominal cavity by combining surgery with heated chemotherapy in the abdominal cavity.

The goal of this treatment is to promote long-term survival or even to cure the patient. The operation is performed under general anesthesia and typically lasts for 6 to 9 hours. However, lengthier procedures may be required.

For Whom?

The HIPEC-treatment is now considered standard of care in many countries for select patients with mesothelioma, pseudomyxoma peritonei and patients with peritoneal cancer from a colorectal tumor. Some hospitals also offer HIPEC treatment for other indications, such as peritoneal cancer from gastric or ovarian cancer.

Post-Operative Course

Since HIPEC is a complex and invasive procedure, postoperative complications occur frequently. Relatively frequent complications include an infection of the lungs or urinary bladder, wound problems and the inability to eat or drink during several days or even weeks.

Treatment After HIPEC and Results

Although the HIPEC procedure is performed with the intent to cure a patient, it should be realized that peritoneal cancer is an aggressive disease, which often recurs even after a successful HIPEC-procedure. To further improve outcomes after HIPEC, the treating physician may advise additional systemic chemotherapy.